Modelling of Signal Transduction Pathways
نویسنده
چکیده
This review focusses on modelling of signal transduction pathways. It will introduce the general concepts of modelling and signal transduction, and then proceed with presenting the two most common approaches: Ordinary Di erential Equations (ODE) and Petri Nets (PN). Including an overview about some of the PN upgrades, such as Timed or Coloured Petri Nets, this review will show the major di erences between those methodologies and elaborate on the (dis-)advantages, as well as discuss some critical decisions in model design.
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